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MENLO PARK, CALIF.--() January 30, 2013 -- Pacific Biosciences of California, Inc. (Nasdaq:PACB) provider of the PacBio® RS High Resolution Genetic Analyzer, today announced it is releasing a new software upgrade that provides higher quality genome assemblies with near perfect base level accuracy in addition to other key features. The software upgrade extends the range of projects that uniquely benefit from the company's Single Molecule, Real-Time (SMRT®) DNA Sequencing method, and will be available to customers for download on January 31st.

SMRT Analysis 1.4 includes a new hierarchical de novo genome assembly process (HGAP), which allows researchers to assemble entire microbial and fungal genomes solely using PacBio long reads. As a result, users can generate better assemblies with a single library preparation and fewer SMRT® Cells than previous approaches that also required short-read sequencing technologies or circular consensus sequencing.

SMRT Analysis 1.4 also incorporates a new multi-read consensus algorithm called Quiver to determine the finished genome sequence with exceptional accuracy. Quiver can provide greater than 99.999% consensus accuracy for both resequencing and de novo assembly applications.

“The extra-long sequence reads and the subsequent highly accurate de novo assemblies produced by the PacBio RS through the latest software enhancements have immensely improved our ability to discover and understand novel genomes cost-effectively,” said J. Craig Venter, Ph.D., Founder, Chairman, and Chief Executive Officer at The J. Craig Venter Institute and CEO of Synthetic Genomics.

The software upgrade also includes support for analyzing full-length cDNA transcripts, facilitating understanding of transcription, gene structure and alternative splicing. Unlike any other sequencing technology, SMRT Sequencing can span entire cDNA transcripts with a single read, revealing the complete exonic structure of transcripts.

Additional features of the new SMRT Analysis 1.4 upgrade include:

· Support for analysis of barcoded samples;

· Improvements to the tools for analyzing and visualizing bacterial methylomes, a capability unique to SMRT Sequencing;

· Enhanced user and group permissions to help sequencing centers and core labs control what data is presented to end users.

“We are committed to continually improving the performance of the PacBio RS, in part through developing software enhancements designed to leverage the unique characteristics of our system,” said Kevin Corcoran, Senior Vice President of Market Development at Pacific Biosciences. “With long sequence reads, gold standard accuracy and higher quality assemblies, the genomics community can enjoy the benefits of truly finished genomes through SMRT Sequencing.”

The new SMRT Analysis software upgrade is available for download from Pacific Biosciences' community website, along with sample data and protocols for cDNA sample preparation and barcoding. To access the software, data, and documentation, visit

For more information on the new SMRT Analysis software and the PacBio RS High Resolution Genetic Analyzer, please visit

About Pacific Biosciences

Pacific Biosciences of California, Inc. (Nasdaq:PACB) offers the PacBio® RS High Resolution Genetic Analyzer to help scientists solve genetically complex problems. Based on its novel Single Molecule, Real-Time (SMRT®) technology, the company's products enable: targeted sequencing to more comprehensively characterize genetic variations; de novo genome assembly to more fully identify, annotate and decipher genomic structures; and DNA base modification identification to help characterize epigenetic regulation and DNA damage. By providing access to information that was previously inaccessible, Pacific Biosciences enables scientists to increase their understanding of biological systems.Korea Newswire distributes your news across every media channels through the industry’s largest press release distribution network

HONG KONG--( / ) January 04, 2016 -- Global nutrition 야동다모아 이민영 company, 남성호르몬수치검사 HONGwelcomes Dr. Francis 바르는정력제 HONGSamonte, an expert in pediatric neurology, to become the first Filipino appointed 맨베스트 박한별제모기 to its prestigious 야동다모아 박한별세븐유출사진 Nutrition Advisory Board (NAB), effective January 1, 2016.



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Samonte’s appointment further strengthens the Herbalife Nutrition Advisory Board members to 30. His addition also reflects further expansion of nutrition and health experts from Asia Pacific 콘돔약국 Samonte’sthe JAVHDHAY Samonte’sAdvisory Board 야동다모아 여교사중학생 who will play a central role in raising 맨베스트 노래잘부르는법 public awareness and leading educational programs on balanced nutrition and healthy active lifestyle in 15 countries across the region as part of Herbalife’s Asia Pacific Wellness Tour initiative.



Samonte is among the Philippines' premier experts in pediatric neurology, and is currently based in Manila. He graduated from De La Salle University College of Medicine in 1995, and has since studied at institutes including John Hopkins University and Harvard Medical School, USA. He was a recipient of the Chairman’s Achievement 야동다모아 찌찌빠빠 Award, Department 옥서면홀덤 SamontePediatrics, University of Louisville, Kentucky, and his 맨베스트 affiliations include the Philippines Medical Association.



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The board 맨베스트 전효성전교3등 is chaired by David Heber, M.D., Ph.D., 야동다모아 Founding Director of the Center for 맨베스트 좋은음악듣기 Human Nutrition at the University of California, Los Angeles (UCLA)*, who was recently in Manila for Herbalife's fourth Asia Pacific Wellness Tour, which included an obesity seminar given to Filipino medical practitioners. Other members of the NAB include Dr. Lou Ignarro, a Nobel** laureate in Physiology or 맨베스트 백점만점송중기 Medicine in 1998 for his discovery of nitric oxide’s health benefits; Dr. Gary Small, a specialist in brain health and aging, who has received numerous awards and honors, including the “Senior Investigator Award” from the American Association for Geriatric 상도2동홀덤대회 The



* 맨베스트 도전1000곡티파니써니 The University of California, as a matter of 야동다모아 정진영 맨베스트 정진영 policy, does not 야동다모아 에스베베 endorse specific products or services. Dr. Heber’s credentials as a professor 야동다모아 핀홀스튜디오 가상화폐리딩 *for identification purposes only.



**The 야동다모아 강심장써니졸업사진 Nobel Foundation 맨베스트 faapy **Theno 야동다모아 옷버스 affiliation with Herbalife and does not review, approve or endorse Herbalife® products. 야동다모아 써니움짤 맨베스트 써니움짤



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Herbalife (NYSE:HLF) is a global nutrition company that sells weight-management, nutrition and personal care products intended to support a healthy lifestyle. Herbalife products are sold in more than 90 countries to and through a network of Independent Herbalife 맨베스트 sexy게임 Members. The company supports the 쎅스 HerbalifeFamily Foundation and its Casa Herbalife Sosocili Herbalifeto help bring good nutrition to children. Herbalife's website 야동다모아 태연키 contains financial 필고 Herbalifeother information about the 맨베스트 송지효글래머 company at



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